1. The Hyuga Clan (also known as the "Byakugan Clan") possesses the ability to manipulate their bones, which is their bloodline limit. They don't need weapons as their tough bones provide excellent defense against any physical attacks. When they attack, their bones transform into powerful spears.
2. The Uzumaki Clan has a long history and, despite their low-profile nature, they couldn't escape the fate of extinction. This is mainly due to their sealing techniques being too powerful, capable of sealing tailed beasts and becoming jinchuriki, which instilled fear in others.
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