1. The First Hokage: Hashirama Senju, or the First Hokage, had the power of Wood Style ninjutsu which could overpower Tailed Beasts. The Nine-Tails would be no match for him.
2. The Second Hokage: Tobirama Senju, the younger brother of the First Hokage, is incredibly strong. Only his brother and Madara Uchiha surpassed his power.
3. The Third Hokage: Hiruzen Sarutobi may not be as powerful as the previous two Hokages. Some consider him the strongest Hokage ever, but he is still weaker than the Tailed Beasts. The outcome of a battle against the Nine-Tails would be uncertain.
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