1. The Sage of the Six Paths: The ancestor of the Uchiha and Senju clans, the Sage created ninjutsu and was the father of Hagoromo Otsutsuki.
2. Uchiha Madara: The leader of the Uchiha clan, Madara became the Ten-Tails Jinchuriki and possessed both Uchiha and Senju powers.
3. Nagato Uzumaki: A member of the Uzumaki clan, Nagato was chosen by Madara to inherit his Rinnegan, a powerful dojutsu.
4. Uchiha Obito: After Nagato's death, Obito stole his Rinnegan and became the Ten-Tails Jinchuriki, surpassing the power of the original Hokage.
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