1. Jiraiya: Jiraiya, one of Konoha's legendary Sannin, ranks equally with Itachi at a power level of 71. Although Jiraiya could potentially put up a good fight against Itachi, he acknowledged his inferiority and retreated from battle when faced with Itachi's strength.
2. Sasuke: Itachi, despite being significantly stronger than Sasuke, never desired to engage in combat with his beloved younger brother.
3. Madara Uchiha: Initially mistaking him for Madara Uchiha, Itachi regarded the masked man with caution. Seeking his assistance during the Uchiha clan massacre, Itachi took precautions by implanting Amaterasu in Sasuke's eyes, anticipating a confrontation with Madara.
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