1. Jiraiya: Jiraiya, one of Konoha's legendary Sannin, ranks equally with Itachi at a power level of 71. Although Jiraiya could potentially put up a good fight against Itachi, he acknowledged his inferiority and retreated from battle when faced with Itachi's strength.
2. Sasuke: Itachi, despite being significantly stronger than Sasuke, never desired to engage in combat with his beloved younger brother. Itachi feared losing Sasuke and the subsequent loneliness and sorrow that would follow if they became enemies. Their brotherly bond meant everything to Itachi.
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