Naruto Uzumaki, the seventh Hokage, is known for his immense strength due to possessing the power of the Six Paths and the nine-tailed beasts. 

Similarly, Uchiha Sasuke's power rivals Naruto's after obtaining the power of the Six Paths and sealing away Kaguya Otsutsuki. 

Kakashi Hatake, the sixth Hokage, is praised for his Sharingan abilities and played a crucial role in sealing Kaguya. Might Guy, Kakashi's good friend, showcases tremendous power during the war but loses his leg. 

Tsunade, one of the legendary Sannin, becomes the fifth Hokage before retiring. 

Orochimaru, initially an antagonist, aligns with Konoha during the Great Ninja War. Kabuto Yakushi, a former subordinate of Orochimaru, obtains immense power and ultimately finds redemption, opening an orphanage in Konoha.